Possibility Of Human Embryo With Three Parents Examined

Technology is taking all efforts to create healthy babies. From animals to humans, more discoveries are coming out in the open. Even in the formation of a human being, science is intervening to prevent deformities in fetuses before their birth.

To remedy thousands of hereditary diseases being transmitted to newly born babies, British scientists are looking into the possibility of creating a human embryo with three parents as a means to correct genetic deformities within five years.

Newcastle researchers in northern England used in vitro fertilization (IVF) or test tube embryos from a male and two other females using a combined DNA and their findings were recently presented at a medical conference in Medical Research Council Centre for Neuromuscular Diseases conference in London.

As a way to prevent mothers from passing on to their offspring possible genetic defects and diseases, this experiment was conducted as mitochondrial DNA deformities responsible for diseases can be eliminated. According to statistics, one in every 5,000 or 0.02 percent of the population of babies being born in the world may suffer from mitochondrial diseases in the form of several diseases such as liver, kidney, heart or brain disorders. Others suffer from speech and hearing impairment or muscular defects or some form of epilepsy.

If this study will be successful, the scientists are looking forward that this will help in providing better techniques in preventing such diseases in new born babies in three to five years from now.
Mitochondria are essential since they are good sources of energy. If they are found faulty, this means they will not be able to use food and oxygen well in the body. As this happens, toxins may build up and later lead to numerous deadly diseases.

Researchers said such instances can be prevented once the embryos with problems are given sufficient attention through mitochondrial transplant. This is done through IVF and the removal of egg's nucleus. The removed DNA can be replaced by healthy DNA from the donor egg.

In the normal setting, the fetus receives nuclear DNA or genes from his biological parents. But with the use mitochondrial DNA, it comes from a third party.

Dr. Patrick Chinnery said it is like taking away the diseased mitochondria and being replaced by healthy ones from a donor.

This study is still in its preliminary stages and will be subject for a series of tests. But other critics are opposing the idea for possible creation of designer babies that might have other problems in the long run.

Maynard Joseph Delfin finished AB Journalism (cum laude) at the University of Santo Tomas. He has worked as book editor, deskman, copy editor and research and publications officer in leading publishing and research companies in the Philippines. Read more of his blogs at http://maynard_delfin.instablogs.com

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